Small business grant

Apply for NIH Small Business Innovation Research (SBIR) – Health

This helper is tailored to National Institutes of Health, the program requirements on file, and the documents listed for this grant.

Max award

$1,000,000

Deadline

April 5, 2027

Agency

National Institutes of Health

Source

federal funding

What this application should emphasize

Use these points to make your draft match this grant instead of sounding like a generic application.

Show the business problem, customer demand, and how funding creates measurable growth.
Use numbers: revenue, jobs, contracts, milestones, or market traction.
Must be a US-based for-profit small business with fewer than 500 employees (SBC — Small Business Concern per SBA standards)
Must be at least 51% owned and controlled by US citizens or permanent residents

Check off each item as you gather it — have these ready before you open the application.

0 of 8 items ready

Download, complete, and save each item before submitting.

0 of 8 ready

PHS 398 Research Plan: Specific Aims, Research Strategy (6 pages Phase I, 12 pages Phase II)

Small Business Certification (SBC) — online in eRA Commons

Commercialization Plan (required for Phase II)

NIH Biosketch for all senior/key personnel (2-page format)

Budget justification using SF-424A or R&R Budget

Letters of support from commercial partners or licensees if applicable

Human subjects or vertebrate animals documentation if applicable

Facilities and Other Resources document

Answer these once — your responses will be used to generate the draft in the next step.